The Role of Peptides ” Messenger Molecules in Advanced Skincare:
Dr Chaithanya R.Peptides were known to have beneficial effects on skin nearly 30 years before their first incorporation into skincare products in 1980s. In 2000s, the first safe peptide was incorporated into skincare, Palmitoyl Pentapeptide. This revolutionary component was safer to use compared to retinol as an anti-ageing product.
Peptides are amino acids linked together by bonds. Peptide are small in size and will penetrate the skin easily and can modulate the cells of the skin to work. Elastin and Collagen are two of the building blocks of skin. They are the ground substances which hold the cells of the skin in place and prevent the appearance of fine lines and wrinkles. As the ageing process continues, the production of both elastin and collagen slows down. Peptides stimulate the skin cells to produce more elastin and collagen. There are many different kinds of peptides which act in many ways.
Peptides have the capacity to stimulate the production of other ground substances such as hyaluronic acid and glycosaminoglycans. Certain amino acids, such as Palmitoyl Pentapeptide, have the capacity to reduce oiliness of skin along with the reduction of wrinkle volume and wrinkle depth. Peptides may also reduce the number of inflammatory cells in the skin. Inflammatory cells cause damage to skin by releasing free radicals. Free radicals have long since been known to cause wrinkles in the skin. Peptides basically act as signal proteins. Palmitoyl Pentapeptide was a peptide that could signal skin cells into believing that the skin was breaking down an accelerated rate and needed urgent repair. This stimulated collagen synthesis.
The peptides being used these days work in 6 different ways. They exfoliate the skin. They cause decreased unnecessary repetitive muscle contractions. They nourish the skin with vital nutrients. They stimulate healthy skin metabolism. They supply sufficient hydration to the skin. They help to maintain healthy collagen matrix. They stimulate the cell turn over.
Another great discovery in the field of cosmeceuticals is the EGF. The full form of EGF is Epidermal Growth Factor. As the name states, EGF causes growth of the epidermis. Epidermis is a part of the skin; it is the most superficial layer. EGF is vital to the maintenance of normal skin. It is released when there is some kind of trauma to the skin. EGF is released from damaged cells and attracts healthy cells to aggregate to the site of trauma and to begin multiplication and repair. This protein is also responsible for the rebuilding of the protein matrix. It also causes increase mitosis as well as neovascularization of the newly created matrix and cells.
Production of this peptide has been known to slow down in the presence of Ultraviolet light. Thus, it can be said that topical application of this growth factor may hugely benefit the reversal or can slow down the process of skin ageing. It may be a good idea to combine EGF with sunscreens to achieve maximum benefit.
From these findings, we can see how vital a role peptides and EGF can play in skincare systems. It may even be the first unsteady beginning of the fountain of youth! EGF and peptides have been considered the future of the skin care as they are the key molecule to signal cell rejuvenation and activate stem cells.RG-Cell serum is the cutting edge skin care line by Timeslip Solutions that contains EGF in the highest concentration on the market and supports a healthy, vibrant skin.
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